ICON Study Evidencing Efficacy of Ivermectin Against COVID-19 Published in Peer Review Journal Chest

Oct 13, 2020 | Blog, Broward County Health, COVID-19, Ivermectin, News, Popular Posts, Positive Results, TSN News

ICON Study Evidencing Efficacy of Ivermectin Against COVID-19 Published in Peer Review Journal Chest

TrialSite News has followed the work of Dr. Jean-Jacques Rajter, Juliana Cepelowicz and team from Broward County Health and their leadership of the ICON study. Initially published via the preprint server, TrialSite proudly announces that the peer-review journal published the results of this important study. Investigating the hypothesis that Ivermectin offers benefit to hospitalized patients with COVID-19, the study team designed and conducted a rigorous and methodical observational study at Broward Health hospitals in Florida. The findings: Ivermectin is associated with lower mortality for those patients infected with SARS-CoV-2, the virus behind COVID-19. The study team found that the already approved and widely used antiparasitic drug was even more effective for those patients experiencing severe pulmonary challenges. Dr. Rajter and team are now seeking to design a randomized controlled trial to confirm these promising findings. With multiple options emerging for the ICON study team, the momentum to investigate Ivermectin as a therapy targeting COVID-19 intensifies in the United States and elsewhere.

TrialSite commends the work of the ICON study team in Florida. Dedicated and committed to individual and population health, this special group has spent months not only working tirelessly to save lives in the Broward Health system but also work overtime to conceive, design, and conduct the ICON study.

Although no decisions have been made as of yet,聽TrialSite聽can report that Dr. Rajter and team have multiple options to pursue participation in a randomized controlled study.聽TrialSite聽also commends the journal聽Chest聽for accepting and ultimately publishing this critically important observational study, offering more real world data indicating the potential of ivermectin as an economical and cost effective treatment option for COVID-19.

Ivermectin Real World Data Accumulating

TrialSite聽has spent the last several聽 months chronicling an accumulating quantity of evidence that Ivermectin should be the basis for a National Institutes of Health (NIH) funded study; in fact聽TrialSite鈥檚聽founder sent an email directly to NIH Director Francis Collins directly suggesting this option. Why? Because after dozens of interviews in India, Bangladesh, Peru, Brazil, Colombia, Dominican Republic, Egypt and the United States, and after an accumulation of several observational studies and the results of at least two randomized controlled trials, there is sufficient evidence to justify at least some public expenditure to pursue this potential therapeutic pathway. It’s economical, widely available and already approved and used by millions around the world.聽

Overcoming COVID-19 will require a multifaceted approach that includes vaccines if they are proven safe and effective, as well as therapies that can help inhibit or prevent the virus replication, to therapies that treat symptoms to improve quality of life. 

About Broward Health Medical Center

 is one of the largest public health systems in America. Located in Broward County, Florida, Broward Health has the country鈥檚 first certified stroke center and liver transplant program.

Lead Research/Investigator

路         Michael S. Sherman, MD, FCCP

路         Naaz Fatteh, MD

路         Fabio Vogel, Pharm D

路         Jamie Sacks, Pharm D

Source:

11 Comments

  1. ML

    I鈥檝e been waiting for this news, TrialSite! Oh, what a happy day to finally see that the Drs Ratjer, are being listened to at last. Now if you and they can only get the NIH to respond… I think that is going to be the biggest hurdle due to the truly enormous profits to be made by investors who instead, are focusing on expensive therapeutics and as yet, unproven vaccines. We want a good vaccine, but we need ones that are very safe, efficacious, and cost-effective. Push, push, push and keep pushing, TSN and Jean Jacque and Juliana! An American public and truly, the entire world will be eternally grateful to all clinicians who practice in the trenches and want to stop the many deaths this terrible scourge has caused humanity. Forge onward!

    Reply
  2. Jason

    Yes. Yes. Yes more than one treatment option is good news for treatment of covid 19. The combo Dr. Alum uses actually behaves like a cure, our government is slow but hopefully they will come around, do the gold standard study an approve it already.

    Reply
    • Drew458

      Who is Dr. Alum please, and what combo is being used? I know of Dr. Borody’s combo, and the Indian version that adds vitamin D to Borody’s mix of Ivermectin, doxycycline and zinc. Dr. Sabine Hazan is using the Indian protocol and adding oral vitamin C. The MATH+ protocol uses intravenous C, with zinc as an option, but no Ivermectin or HCQ.

      Reply
  3. Paul Elkins

    Many thanks for Trial Site News’ persistence in not allowing Ivermectin to be ignored! Doctors like the Rajters and others serve as a strong example that Ivermectin is a safe and effective therapeutic to use off label in the fight against covid-19 while larger RCTs are still running. As Trial Site News has reported there are a multitude of very positive data points including at least two international RCTs. Combined with the excellent safety profile Ivermectin should be leveraged ASAP in the fight against Covid-19!

    The FDA should issue an EUA and the NIH should include IVM in their Treatment Guidelines ASAP while we await additional RCT results. In the meantime frontline clinicians can feel more confident prescribing off-label with the peer reviewed data from the ICON study along with the RCTs and RWE.

    Reply
  4. Ron Carson

    Isn鈥檛 the university of Kentucky already a trial on ivermectin. They announced it in May. It should be getting close to completion by now.

    Reply
    • James Lamar

      The study completion date is May 2021. It’s listed on clinicaltrial.gov site.

      Reply
  5. Walt

    With all the existing studies including 2 RCT鈥檚 and many observational studies, Ivermectin should now be approved. I believe that performing another RCT is a waste of time , resources, and is unethical. Unethical because the preponderance of evidence shows that Ivermectin is effective and we know it is safe. Therefore how do we give a group of sick patients a placebo knowing that their odds of dieing or becoming seriously ill are significantly reduced if they are given Ivermectin. Further we know what the likely course of this disease is, we know how many will survive and how many will die with statistical precision without the use of a placebo arm.

    Reply
    • john

      I love your analysis. FDA is complicit in the deaths of the.
      untreated

      Reply
  6. jim goodyear

    Thank you trialsite for your excellent coverage of Ivermectin. I truly hope it is determined that it works can be used as what could be labeled as a cure. Please all keep in mind that I believe the original discovery that Ivermectin was actually useful against covid originated in Australia at Monash University and further enhanced by Dr Thomas Borody of Australia by combining it with Doxicycline and Zink. Please give credit where credit is due. Borody also initiated a clinical trial ongoing in California by Dr Sabine Hazan. Thanks to all the open minded medical professionals who are trying this therapeutic and giving more proof that it works. There seems to be many who are not so open minded.

    Reply
  7. Tanya

    Thank you TrialSiteNews for keeping the spotlight on ivermectin, lest it gets buried and forgotten. When i search for info about ivermectin, the only thing cdc and other govt websites say is that it is not recommended.

    Reply
    • john

      “Not recommended” shows their allegiance to BigPharma

      Reply

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